Hi, I am the proud mother of two children with trisomy 21. Mikayla is 12 and Nathan is almost 8. They are beautiful and the loves of my life. I knew before both of them were born that they had DS. I go to the doctor tomorrow and will be scheduling an appointment with a specialist very very soon. I know that the life I am carrying is perfect because he/she is God's design, but it is still very difficult. Does anyone out there know of anyone having 3 children with Down Syndrome? Again, both of my children have trisomy 21 and it is not genetically linked to me. This little one has a different daddy so maybe that will make a difference -- not sure. I guess I just need some positive support right now. I'm trying to stay positive, but its hard.