Amber- I know how you feel. It's a difficult decision. You've been very strong to go through what you've been through. I've have 5 m/c and 2 live births in the past 4 years. I've been through all the emotions. I've always just kept on trying. We haven't prevented in 4 years. It's been very hard on us but we can't help but continue to try for the family we've always hoped for... at this point as many as we can be blessed with. We are both 1 of 5 kids and want the same for our children. I was at a friend's home recently (who has 2 children through IVF because of blocked tubes... 2nd child born the day after my most recent D&C) and another close friend of hers was over. This woman had 3 children and she suffered preterm labor with all of them as early as 20 weeks with bedrest during pretty much her entire pregnancies. She said she always wanted 4 children but she and her husband decided they didn't want to put another child at risk. I suddenly felt so guilty... for trying to create the family my husband and I always wanted... I'm creating and risking so many lives. Am I being selfish? I talked to my friend about this and she always knows how to make me feel better. I can't recall exactly what she said but she definitely helped me to see that I want to keep trying. I still have no answers to why my babies don't survive but I'm going to keep trying... I have a great doctor and supportive husband who wants more children too and beautiful babies that motivate me and that I want to give more siblings to :) ... all that's left is to make it happen. Only time will tell. I'm not sure what MTHFR is but I'm glad you have some answers! I think you should do whatever you decide you want. My choice to keep trying, I'm sure, will bring more loss and pain in the future but it'll be worth it in the end. I have had children and know I can have more. I'll never wish we hadn't kept trying... if all we have is more losses... well, my heart is already broken and I'm so glad my girls have each other. But I would always wonder and possibly regret if I didn't keep trying. My feelings seem to change back and forth right when I have my losses but I always come back to trying. Don't feel like you need to make this huge decision right now and if you change your mind, that's ok. Things change... and sometimes for the good :) I'm so sorry for your losses. I wish you luck and you'll be in my thoughts.